FluMist, an intranasal spray for the flu.measles, mumps, and rubella (MMR) vaccine.Using either Enbrel or Humira with the following live vaccines increases your risk of severe infection: In addition, interactions can be harmful or prevent the drugs from working well. This can help prevent possible drug interactions, which can change how your drug works. However, there still may be a risk of non-melanoma skin cancer, especially squamous cell cancer.Īs a result, it’s a good idea for all patients using TNF-alpha inhibitors to get a yearly skin check with a dermatologist.Īlways let your doctor or pharmacist know about all medications, vitamins, or herbs you’re taking. Lastly, a 2019 Lancet study demonstrated that TNF-alpha inhibitors did not increase the risk of primary types of cancer, such as lymphoma. Before this change, those using Humira were over three times as likely to report injection-site burning and stinging. To reduce injection site reactions, the manufacturer of Humira reformulated the product to a citrate-free formulation. liver problems like yellowing of skin and eyes, bruising, or bleeding easily.serious infections such as tuberculosis (TB)or hepatitis-B.blood problems like low white blood cells and low platelets.nervous system problems like weak arms or legs, numbness, tingling, dizziness.serious bacterial, viral, or fungal infections.Some of the more common side effects include: As a result, they have similar side effects. until 2029.Įnbrel and Humira belong to the same drug class. Even so, because of Enbrel’s drug patent, they may not be available in the U.S. The biosimilars of Enbrel are Erelzi and Eticovo. Seven other biosimilars of Humira have been approved by the FDA but will not be released until mid-2023:Īdditional biosimilars of Humira are pending FDA approval. One Humira biosimilar, Amjevita, became available in U.S. Once they become widely available, biosimilars may be more affordable than the original brand-name drug. You can call your local pharmacy to see if they have Enbrel or Humira in stock and if they can dispense them.īiosimilars are available for both drugs. They may also need a specific kind of storage. These drugs treat certain complex conditions and may have particular instructions for use and monitoring side effects. This is because both medications are considered specially drugs. However, to dispense them, they will need to have special pharmacy divisions. Many pharmacies carry both Enbrel and Humira. Your pharmacy can help you with the paperwork if authorization is needed. Check with your insurance company or pharmacy to determine whether you need prior authorization for Enbrel or Humira. Many insurance providers require prior authorization from your doctor before paying for either of these drugs. How each person responds to either drug will vary.Įnbrel and Humira are only available as brand-name drugs, not generics, and they cost about the same.Ĭalling your prescription insurance company can give you a more specific idea about their current costs. Yet, an adequate trial of the drugs is about 3 months to see the full benefit. People will typically see some improvement with either drug after two to three doses. You may find that the Enbrel AutoTouch or SureClick Autoinjector and Humira prefilled pens are easier and more convenient to use than single-dose vials and prefilled syringes. Once per week (initially twice weekly for some conditions)
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